Adaptimmune Therapeutics

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Brand information:

Website	Adaptimmune Therapeutics
Country	United Kingdom
Industry	Pharmaceuticals

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Adaptimmune is a leader in TCR T-cell therapy, focused on designing and delivering novel cancer immunotherapy products. We utilize the body’s own machinery – the T-cell – to target and destroy cancer cells. We believe our therapies have the potential to significantly impact cancer treatment and clinical outcomes of people with cancer.

We have developed a proprietary T-cell receptor (TCR) platform that enables us to identify cancer targets, as well as find and genetically engineer TCRs to recognize and attack these targets. We engineer a patient’s own T-cells to express these affinity-enhanced TCRs, to produce TCR T-cell treatments that we call SPEAR (Specific Peptide Enhanced Affinity Receptor) T-cell therapies. We plan on submitting our first Biologics License Application (BLA) by the end of 2022 for afamitresgene autoleucel (“afami-cel”; formerly ADP-A2M4) for the treatment of people with synovial sarcoma.

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